The Patel laboratory asks fundamental questions about how the liver works, and by doing so we hope to gain new insights into the metabolic causes and consequences of liver disease with the ultimate goal of developing new clinical therapies.

 

Our laboratory has a particular interest in hepatic metabolism and its regulation by the immune system. We utilize genetic, epigenetic and proteomic approaches, combined with detailed physiological studies, to understand the complex mechanisms that causally link inflammation to metabolic dysfunction in obesity and fatty liver disease.